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workshop:2016:questions [2016/03/11 15:58] lessem [Questions and Answers] |
workshop:2016:questions [2016/03/11 16:25] 65.114.233.215 [Questions/comments from Friday] |
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??? 11. If we get a code Mx status RED, what do we need to do/consider (in general)? E.g., are our model estimates still reliable? | ??? 11. If we get a code Mx status RED, what do we need to do/consider (in general)? E.g., are our model estimates still reliable? | ||
!!! Rob K. says: Status RED means the optimizer is not certain it has found a minimum of the fitfunction. | !!! Rob K. says: Status RED means the optimizer is not certain it has found a minimum of the fitfunction. | ||
- | * If you're analyzing ordinal data, sometimes a status RED is unavoidable without changing some [[http:// | + | * If you're analyzing ordinal data, sometimes a status RED is unavoidable without changing some [[http:// |
* Use different start values. | * Use different start values. | ||
* Try a different optimizer. | * Try a different optimizer. | ||
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???13. What is the difference in interpretation between GCTA h2 estimates and LD score regression h2 estimates? | ???13. What is the difference in interpretation between GCTA h2 estimates and LD score regression h2 estimates? | ||
!!!MCK: I'll let Ben weigh in as well. But in essence, they should be two different ways of estimating the *same* parameter: SNP-heritability. I think that the differences in the literature are about what we'd expect given the SE's on the estimates. Ben - are there any systematic differences between the two? | !!!MCK: I'll let Ben weigh in as well. But in essence, they should be two different ways of estimating the *same* parameter: SNP-heritability. I think that the differences in the literature are about what we'd expect given the SE's on the estimates. Ben - are there any systematic differences between the two? | ||
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+ | ??? 14. @Sarah where can we find the full syntax of this morning' | ||
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+ | ??? 15. Where can researchers find publicly available twin data? | ||
+ | !!! One place a researcher can begin searching for publicly available data is the repository developed and managed by the Inter-university Consortium for Political and Social Research (ICPSR). | ||
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+ | As an aside, another publicly available resource towards developing harmonized measures of biomedical phenotypes is the PhenX toolbox (https:// | ||
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====== Questions/ | ====== Questions/ |