******************************************************************* * Genome-wide Complex Trait Analysis (GCTA) * version 1.92.0 beta2 * (C) 2010-2018, The University of Queensland * Please report bugs to: Jian Yang ******************************************************************* Analysis started at 14:39:22 UTC on Tue Mar 05 2019. Hostname: workshop-11 Accepted options: --grm mydata_allSNPs --pheno mydata.phen --mpheno 2 --reml --keep unrelated.singleton.txt --out trait2_allSNPs Note: the program will be running on 4 threads. Reading IDs of the GRM from [mydata_allSNPs.grm.id]. 6000 IDs read from [mydata_allSNPs.grm.id]. Reading the GRM from [mydata_allSNPs.grm.bin]. GRM for 6000 individuals are included from [mydata_allSNPs.grm.bin]. Reading phenotypes from [mydata.phen]. There are 2 traits specified in the file [mydata.phen]. Trait #2 is included for analysis. Non-missing phenotypes of 6000 individuals are included from [mydata.phen]. 4808 individuals are kept from [unrelated.singleton.txt]. 4808 individuals are in common in these files. Performing REML analysis ... (Note: may take hours depending on sample size). 4808 observations, 1 fixed effect(s), and 2 variance component(s)(including residual variance). Calculating prior values of variance components by EM-REML ... Updated prior values: 0.501648 0.507082 logL: -2266.63 Running AI-REML algorithm ... Iter. logL V(G) V(e) 1 -2266.11 0.49555 0.51406 2 -2265.88 0.48143 0.52999 3 -2265.64 0.47955 0.53153 4 -2265.64 0.47935 0.53168 5 -2265.64 0.47933 0.53170 Log-likelihood ratio converged. Calculating the logLikelihood for the reduced model ... (variance component 1 is dropped from the model) Calculating prior values of variance components by EM-REML ... Updated prior values: 0.99804 logL: -2403.01250 Running AI-REML algorithm ... Iter. logL V(e) 1 -2403.01 0.99804 Log-likelihood ratio converged. Summary result of REML analysis: Source Variance SE V(G) 0.479330 0.031773 V(e) 0.531696 0.024740 Vp 1.011026 0.022118 V(G)/Vp 0.474102 0.026153 Sampling variance/covariance of the estimates of variance components: 1.009536e-03 -5.662076e-04 -5.662076e-04 6.120842e-04 Summary result of REML analysis has been saved in the file [trait2_allSNPs.hsq]. Analysis finished at 14:42:37 UTC on Tue Mar 05 2019 Computational time: 3 minutes 15 second(s).