Mach 1.0.18.c -- Markov Chain Haplotyping (c) 2005-2007 Goncalo Abecasis, with thanks to Yun Li, Paul Scheet The following parameters are in effect: Available Options Input Files : --datfile [myers22flipped.dat], --pedfile [myers22flipped.ped], --mask [0.00] Optional Files : --crossoverMap [], --errorMap [], --physicalMap [] Phased Data : --snps [], --haps [], --hapmapFormat, --vcfReference, --autoFlip, --greedy Regional Options : --startposition [0.00], --endposition [300000000.00] Markov Sampler : --seed [123456], --burnin, --rounds [20] Mapping Options : --npl, --association Haplotyper : --states [200], --errorRate [1.0e-03], --weighted, --compact Imputation : --forceImputation, --geno, --quality, --dosage, --probs, --mle Output Files : --prefix [myers22flipped.haps], --phase [ON], --uncompressed, --mldetails Interim Output : --sampleInterval, --interimInterval WARNING: no reference haplotypes provided. Count number of markers in the sample marker information file ... Read 5405 markers from sample marker information file Loaded pedigree with: 193 individuals to be haplotyped at 5405 markers Formating genotypes and allocating memory for haplotyping Pedigree file ... 3.0 mb Haplotyping engine (max) ... 418.7 mb Haplotyping engine (actual) ... 416.4 mb Consensus builder ... 8.0 mb Memory allocated successfully Found initial haplotype set Markov Chain iteration 1 [63888 mosaic crossovers] Markov Chain iteration 2 [72563 mosaic crossovers] Markov Chain iteration 3 [77366 mosaic crossovers] Markov Chain iteration 4 [80657 mosaic crossovers] Markov Chain iteration 5 [82339 mosaic crossovers] Markov Chain iteration 6 [84515 mosaic crossovers] Markov Chain iteration 7 [86322 mosaic crossovers] Markov Chain iteration 8 [87430 mosaic crossovers] Markov Chain iteration 9 [88459 mosaic crossovers] Markov Chain iteration 10 [89511 mosaic crossovers] Markov Chain iteration 11 [90161 mosaic crossovers] Markov Chain iteration 12 [90693 mosaic crossovers] Markov Chain iteration 13 [91253 mosaic crossovers] Markov Chain iteration 14 [91506 mosaic crossovers] Markov Chain iteration 15 [91654 mosaic crossovers] Markov Chain iteration 16 [91812 mosaic crossovers] Markov Chain iteration 17 [92002 mosaic crossovers] Markov Chain iteration 18 [91769 mosaic crossovers] Markov Chain iteration 19 [91877 mosaic crossovers] Markov Chain iteration 20 [91817 mosaic crossovers] Merged sampled haplotypes to generate consensus Consensus estimated to have 4185.9 errors in missing genotypes and 30014.2 flips in haplotypes Wrote out file [myers22flipped.haps.gz] with phased chromosomes ... Wrote out file [myers22flipped.haps.rec] with mosaic crossover rates ... Wrote out file [myers22flipped.haps.erate] with per marker error rates ... Estimated mismatch rate in Markov model is: 0.00140 Analysis took 4047 seconds